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Genetics, Biotechnology & Nanotechnology MCQ - Practice Questions with Answers

Solve 218 Genetics, Biotechnology & Nanotechnology questions for RAS/RPSC preparation.

Practice questions

Q1Rare gynandromorph specimens of the freshwater crab species Vela carli were reported from which country?

A Australia
B Brazil
C India
D Indonesia
Explanation

Researchers reported gynandromorphy in Vela carli, a freshwater crab species from Silent Valley National Park in Kerala, India. The finding concerns rare male-and-female traits in specimens of a known species, not the discovery of a completely new species.

Q2Which sector is the largest contributor to India's bioeconomy?

A BioPharma ($64.5 billion)
B BioIndustrial ($90.2 billion)
C BioAgri ($14.6 billion)
D BioServices ($26 billion)
Explanation

BioIndustrial leads India's bioeconomy at $90.2 billion, followed by BioPharma ($64.5 billion), BioServices ($26 billion), and BioAgri ($14.6 billion).

Q3The Human Genome Project was completed in which year?

A 2010
B 2000
C 1998
D 2003
Explanation

The Human Genome Project was completed in April 2003, mapping approximately 20,000-25,000 human genes and sequencing 3 billion DNA base pairs.

Q4Consider the following statements: 1. Genome sequencing reveals the complete DNA sequence and helps identify disease-causing mutations. 2. The IndiGen programme sequenced 10,029 Indian genomes. 3. mRNA vaccines deliver genetic instructions for cells to produce a target antigen and do not use live, weakened or inactivated virus. 4. mRNA in such vaccines is described as degrading within days. Which of the statements given above are correct?

A 1, 3 and 4 only
B 1 and 2 only
C 2, 3 and 4 only
D 1, 2, 3 and 4
Explanation

Statement 1 is correct because genome sequencing reveals the complete DNA sequence and supports identification of disease-causing mutations. Statement 2 is incorrect because the IndiGen programme sequenced 1,029 Indian genomes, not 10,029. Statement 3 is correct because mRNA vaccines supply instructions to produce an antigen and do not use live, weakened or inactivated virus. Statement 4 is correct because mRNA degrades within days.

Q5Consider the following statements: 1. Genome sequencing can help identify disease-causing mutations and genetic risk factors. 2. Nanotechnology always makes materials behave exactly like bulk materials. 3. CAR-T cell therapy involves extracting a patient's T-cells, genetically engineering them to attack cancer cells and infusing them back into the patient. Which of the statements given above are correct?

A 1 and 3 only
B 1 and 2 only
C 2 and 3 only
D 1, 2 and 3
Explanation

Statements 1 and 3 are correct. Statement 2 is incorrect because nanoscale materials can show different physical, chemical or biological properties from larger-scale materials.

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6Consider the following statements: 1. Nanotechnology typically deals with materials at the scale of 1-100 nanometers. 2. India's Nano Mission was launched in 2007 and is coordinated by the Department of Science and Technology. 3. Biosimilars are exactly identical to reference biologics because they are simple chemical copies. Which of the statements given above are correct?

A1 and 3 only
B2 and 3 only
C1 and 2 only
D1, 2 and 3

7Consider the following statements: 1. CRISPR-Cas9 can add, delete or alter specific DNA sequences. 2. Plant tissue culture can produce uniform, disease-free plants under sterile laboratory conditions. 3. ZyCoV-D was the world's first DNA plasmid-based COVID-19 vaccine. Which of the statements given above are correct?

A1 and 2 only
B2 and 3 only
C1 and 3 only
D1, 2 and 3

8Consider the following statements: 1. Graphene is a single layer of carbon atoms arranged in a two-dimensional hexagonal lattice. 2. Graphene has excellent electrical and thermal conductivity. 3. Graphene is a single layer of silicon atoms arranged in a circular lattice. Which of the statements given above are correct?

A1 only
B3 only
C1 and 2 only
D1, 2 and 3

9CRISPR-Cas9 gene editing technology works by:

AExposing DNA to radiation
BChemical modification of proteins
CInserting foreign DNA randomly
DUsing a guide RNA to direct Cas9 enzyme to cut DNA at specific locations

10Consider the following statements about CRISPR-Cas9: 1. It is a gene-editing tool that allows precise modification of DNA sequences in living organisms. 2. It was developed by Jennifer Doudna and Emmanuelle Charpentier. 3. The Nobel Prize associated with it was awarded in 2012. Which of the statements given above are correct?

A1 and 2 only
B2 and 3 only
C1, 2 and 3
D1 and 3 only

11Biosimilars differ from generic drugs in that:

AThey are produced only from plant sources
BThey are chemically identical copies of small-molecule drugs
CThey have no regulatory approval process
DThey are similar but not identical copies of complex biological medicines

12Nano-silver particles are widely used for their:

AAntimicrobial properties
BMagnetic properties
CRadioactive properties
DInsulation properties

13BIRSA 101 gene therapy uses which genome-editing technology?

ABase Editing
BCRISPR-Cas9
CTALENs
DZinc Finger Nuclease

14Specimens of the freshwater crab species Vela carli recently observed in Silent Valley National Park exhibited which rare biological condition?

ABioluminescence
BParthenogenesis
CGynandromorphism
DHermaphroditism

15Consider the following statements: 1. Quantum dots are semiconductor nanocrystals of about 2-10 nm that emit light of specific wavelengths depending on size. 2. Carbon nanotubes are cylindrical molecules made from rolled graphene sheets. 3. Carbon nanotubes are described as 100 times stronger than steel at one-sixth the weight. 4. Silver nanoparticles are mainly valued because they are biologically inert and lack antimicrobial properties. Which of the statements given above are correct?

A1 and 2 only
B2 and 4 only
C1, 2 and 3 only
DAll four

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