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Human body, blood groups, genetics and common diseases MCQ - Practice Questions with Answers

Solve 11 Human body, blood groups, genetics and common diseases questions for RAS/RPSC preparation.

Practice questions

Q1List I: 1. Gene 2. Genome 3. Mutation 4. Autosome List II: a. Change in genetic material b. Functional stretch of DNA c. Total hereditary material d. Non-sex chromosome pair Choose the correct matching.

A 1-b, 2-c, 3-a, 4-d
B 1-c, 2-b, 3-a, 4-d
C 1-b, 2-a, 3-c, 4-d
D 1-d, 2-c, 3-a, 4-b
Explanation

The basic genetics terms carefully are distinct. A gene is a functional stretch of DNA, while a genome is the total hereditary material of an organism. Mutation means a change in genetic material. Humans normally have 23 chromosome pairs, of which 22 pairs are autosomes and one pair is sex chromosomes, so an autosome is a non-sex chromosome pair in this school-level framing. The matching that keeps these definitions separate is gene to functional DNA stretch, genome to total hereditary material, mutation to genetic change, and autosome to non-sex chromosome pair.

Q2Assertion (A): Maintaining blood glucose within a stable range is an example of homeostasis. Reason (R): Homeostasis means maintaining a stable internal environment despite outside change.

A Both A and R are true, but R does not explain A.
B Both A and R are true, and R explains A.
C A is true, but R is false.
D A is false, but R is true.
Explanation

Homeostasis is the body’s regulation of a stable internal environment even when outside conditions change. Body temperature and blood glucose are given as examples of such control. Therefore, keeping blood glucose within a stable range is not just a random body function; it is a direct case of homeostasis. The reason states the general rule, and the assertion gives one example of that rule. This makes both statements true, with the reason correctly explaining the assertion.

Q3Statement 1: A gene is a functional stretch of DNA, while a genome is the total hereditary material. Statement 2: A dominant allele is always common and beneficial in a population. Which of the above statements is/are correct?

A Statement 1 only
B Statement 2 only
C Both Statement 1 and Statement 2
D Neither Statement 1 nor Statement 2
Explanation

The genetics notes make a precise vocabulary distinction: a gene is a functional stretch of DNA, and a genome is the total hereditary material of an organism. They also warn against a common examination error: a dominant trait is not automatically common or beneficial. Dominance only means that an allele can show its effect in a heterozygous condition. Therefore, the gene-genome statement is correct, but the statement about dominant alleles being always common and beneficial is not.

Q4Which statement correctly distinguishes breathing from cellular respiration?

A Breathing releases energy inside cells, while cellular respiration only moves air in and out of the lungs.
B Breathing moves air in and out of the lungs, while cellular respiration releases energy in cells.
C Breathing and cellular respiration are the same process because both only exchange oxygen and carbon dioxide.
D Breathing filters blood in the kidneys, while cellular respiration transports oxygen through haemoglobin.
Explanation

CET questions often confuse breathing with cellular respiration. Breathing is the mechanical movement of air in and out of the lungs. Cellular respiration is the process by which energy is released inside cells. Kidney filtration, haemoglobin transport and general gas exchange are related body functions, but they do not define this specific contrast. Therefore the correct distinction is that breathing moves air, while cellular respiration releases energy in cells.

Q5How many genotypes of the human ABO blood group are possible?

A 4
B 6
C 3
D 8
Explanation

The human ABO blood group is controlled by three alleles: IA, IB and i. A genotype is formed by taking two alleles at a time. The possible combinations are IAIA, IAi, IBIB, IBi, IAIB and ii, giving six genotypes in total. Four refers to the phenotypes A, B, AB and O, not genotypes. Three counts only the alleles. Eight is too high because the same two-allele combinations are not counted separately by order.

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More questions

6Statement 1: In the ABO system, group AB has both A and B antigens on red blood cells. Statement 2: In the ABO system, group O has both A and B antigens on red blood cells. Which of the following is correct?

AStatement 1 is correct, but Statement 2 is incorrect.
BStatement 1 is incorrect, but Statement 2 is correct.
CBoth statements are correct.
DBoth statements are incorrect.

7A village reports many diarrhoea cases after unsafe water use., which response most directly reduces waterborne infection risk before medicines are needed?

AUsing ORS because it kills cholera bacteria in the intestine
BGiving antibiotics for every fever because fever proves a bacterial infection
CBoiling or safely treating drinking water
DOnly isolating patients, because all diarrhoea mainly spreads through air

8Assertion (A): Body Mass Index is calculated as weight in kilograms divided by height in metres squared, and it is used to screen thinness, overweight and obesity. Reason (R): Body Mass Index diagnoses micronutrient deficiency because it directly measures haemoglobin and vitamin levels. Choose the correct answer.

ABoth the assertion and the reason are true, and the reason correctly explains the assertion.
BBoth the assertion and the reason are true, but the reason does not correctly explain the assertion.
CThe assertion is false, but the reason is true.
DThe assertion is true, but the reason is false.

9Match List I with List II. List I: 1. Innate immunity 2. Active immunity 3. Passive immunity 4. Antibiotics List II: a. Ready-made antibodies b. First, non-specific defence c. Body produces its own response after infection or vaccination d. Act against bacteria or related biological processes

A1-a, 2-b, 3-c, 4-d
B1-c, 2-a, 3-b, 4-d
C1-b, 2-c, 3-a, 4-d
D1-b, 2-d, 3-c, 4-a

10Which one of the following statements about food safety is incorrect?

AThe Food Safety and Standards Act, 2006 created the FSSAI-led framework for science-based food standards in India.
BPasteurisation reduces harmful microbes in milk and makes careless storage safe forever.
CFood hazards may be biological, chemical or physical.
DAdulteration usually implies prohibited addition, substitution or removal, while contamination can also be accidental.

11Which blood-group statement is correct for the ABO system and routine teaching of red-cell transfusion?

AGroup O has both A and B antigens and no anti-A or anti-B antibodies.
BGroup AB has neither A nor B antigen and is therefore often called the universal donor.
CThe Rh factor is only another name for the ABO system.
DO negative is often called the universal donor, but safe transfusion still requires cross-matching and medical supervision.

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