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Human body, blood groups and common diseases MCQ - Practice Questions with Answers

Solve 10 Human body, blood groups and common diseases questions for RAS/RPSC preparation.

Practice questions

Q1Assertion (A): Incompatible blood transfusion can cause red blood cells to clump dangerously. Reason (R): ABO blood groups are based on antigens on red blood cells and antibodies in plasma. Choose the correct answer.

A Both the assertion and the reason are true, and the reason correctly explains the assertion.
B Both the assertion and the reason are true, but the reason does not explain the assertion.
C The assertion is true, but the reason is false.
D The assertion is false, but the reason is true.
Explanation

ABO groups depend on which antigens are present on red blood cells and which antibodies are present in plasma. If incompatible blood is given, these antibodies can react with unmatched red-cell antigens and cause agglutination, meaning red cells clump together. That clumping may produce a dangerous transfusion reaction. Therefore the assertion about unsafe clumping is true, and the antigen-antibody basis of ABO grouping gives the direct reason for it.

Q2Assertion (A): Completing the full treatment course in tuberculosis is important. Reason (R): Irregular TB treatment can lead to drug resistance. Choose the correct answer.

A Both the assertion and the reason are true, but the reason does not explain the assertion.
B The assertion is true, but the reason is false.
C Both the assertion and the reason are true, and the reason explains the assertion.
D The assertion is false, but the reason is true.
Explanation

The communicable-disease section treats tuberculosis as a disease where the prevention and control logic includes early diagnosis and complete treatment. It then gives the reason: in TB, completing the full treatment course is essential because irregular treatment can lead to drug resistance. The assertion that the full course matters is therefore true, and the reason is also true. More importantly, the reason directly explains the assertion by linking incomplete or irregular treatment with the danger of drug resistance.

Q3Which statement correctly describes vaccination as explained?

A It kills the present infection directly in the same way as an antibiotic.
B It exposes the immune system to a safe form, part or instruction related to a pathogen so that the body can respond faster later.
C It replaces safe water, sanitation and handwashing in disease control.
D It works only after the full disease has already occurred.
Explanation

The immunisation section defines a vaccine as exposure to a safe form, part or instruction related to a pathogen. The purpose is to train the immune system so that the body can respond faster during a later infection. This is different from saying that a vaccine directly kills a current infection like an antibiotic. Vaccination also sits alongside hygiene, safe water, sanitation, surveillance and treatment, so it does not replace those measures. The correct description is preventive immune preparation.

Q4Which disease-route pair is correctly stated?

A Cholera - mainly spreads through the bite of infected female Anopheles mosquitoes
B Tuberculosis - mainly spreads through unsafe drinking water
C Dengue - spreads through Aedes mosquitoes, often breeding in clean stagnant water near homes
D Malaria - spreads through Aedes mosquitoes that breed in clean stagnant water near homes
Explanation

Learning communicable diseases by pathogen type and route of spread. Dengue is described as a viral disease spread by Aedes mosquitoes, which often breed in clean stagnant water near homes. Malaria is different: it is caused by Plasmodium parasites and spreads through infected female Anopheles mosquitoes. Cholera is a bacterial water-borne disease linked with unsafe water and sanitation, while tuberculosis is linked with airborne or droplet spread. The dengue-Aedes-clean-stagnant-water pairing is therefore the correctly stated route.

Q5Consider the following statements about the ABO and Rh blood-group systems. Statement 1: In the ABO system, group O has neither A nor B antigen on red blood cells. Statement 2: The Rh system adds the positive or negative layer depending on whether the Rh antigen is present. Which of the statements is/are correct?

A Both Statement 1 and Statement 2
B Statement 1 only
C Statement 2 only
D Neither Statement 1 nor Statement 2
Explanation

The two layers separately. In the ABO system, group A has A antigen, group B has B antigen, group AB has both, and group O has neither A nor B antigen on red cells. The Rh system is another layer: when the Rh antigen is present, the blood group is positive; when it is absent, the group is negative. Since both statements reproduce these rules, the correct response accepts both. This is the reason blood banks record combinations such as A positive or O negative.

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More questions

6Which blood component is correctly matched with its main function?

AWhite blood cells - transport oxygen with haemoglobin
BRed blood cells - transport oxygen
CPlatelets - carry hormones and nutrients in solution
DPlasma - form clots after injury

7List I gives nutrients and List II gives deficiency diseases. Choose the correctly matched set. List I: Iron, iodine, vitamin A, vitamin C List II: Anaemia, goitre, night blindness, scurvy

AIron - goitre; iodine - anaemia; vitamin A - scurvy; vitamin C - night blindness
BIron - anaemia; iodine - scurvy; vitamin A - goitre; vitamin C - night blindness
CIron - night blindness; iodine - goitre; vitamin A - anaemia; vitamin C - scurvy
DIron - anaemia; iodine - goitre; vitamin A - night blindness; vitamin C - scurvy

8Which part of blood mainly transports oxygen in the human body?

APlasma
BRed blood cells
CWhite blood cells
DPlatelets

9Consider the following statements about digestion: Statement 1: Digestion begins in the mouth, where chewing and saliva start breaking down food. Statement 2: The small intestine is the main site of digestion and absorption. Which statement is correct?

AOnly Statement 1
BOnly Statement 2
CBoth Statement 1 and Statement 2
DNeither Statement 1 nor Statement 2

10Match the deficiency with the disease most directly linked. List I: 1. Iron deficiency 2. Iodine deficiency 3. Vitamin A deficiency 4. Vitamin C deficiency List II: a. Goitre b. Scurvy c. Anaemia d. Night blindness

A1-a, 2-b, 3-c, 4-d
B1-b, 2-a, 3-d, 4-c
C1-c, 2-d, 3-a, 4-b
D1-c, 2-a, 3-d, 4-b

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