The WHO Global Tuberculosis Report 2025, released on November 12, 2025, confirmed that India continues to bear the world's highest TB burden at 25% of global cases, with an estimated 10.7 million people affected globally in 2024 and TB claiming 1.23 million lives worldwide. However, India has made significant strides: TB incidence fell from 237 per lakh in 2015 to 187 per lakh in 2024 — a 21% reduction, nearly double the global pace of decline. Mortality dropped from 28 per lakh (2015) to 21 per lakh (2024), and treatment coverage improved from 53% to 92% over the same period. Despite this progress, India remains far from the WHO End TB Strategy targets of 80% incidence reduction and 90% mortality reduction by 2030. About one lakh TB cases remain 'missing' — undiagnosed and unreported — continuing to fuel transmission. India also accounts for 8.8% of the global TB detection gap, second only to Indonesia. The WHO flagged that funding challenges globally could reverse hard-won gains. India's Pradhan Mantri TB Mukt Bharat Abhiyan (launched 2022), Nikshay Poshan Yojana, and Universal Drug Susceptibility Testing (UDST) are key programme initiatives. The government has set a target to eliminate TB from India by 2025 — five years ahead of the global target — though the report signals this deadline may not be met.