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RAS question

mRNA technology works by:

Correct answer: (B) Providing instructions to cells to make specific proteins temporarily.

mRNA technology works by giving cells temporary instructions to make specific proteins, such as the spike protein used in COVID-19 vaccines.

  1. (A)

    Inserting DNA into host cells permanently

  2. (B)

    Providing instructions to cells to make specific proteins temporarily

  3. (C)

    Killing viruses directly

  4. (D)

    Replacing the immune system

Explanation

mRNA, or messenger RNA, technology does not permanently change a cell. It delivers synthetic, laboratory-created mRNA into cells, where the cell machinery reads those instructions and makes a target protein. In COVID-19 mRNA vaccines, that target is a harmless piece of the spike protein. The displayed protein then helps trigger an immune response, including antibody production. This is why the best description is temporary instruction-giving, not DNA insertion or direct virus killing. The CDC source also notes that cells break down the vaccine mRNA within a few days and that it does not enter the cell nucleus where DNA is located. Katalin Kariko and Drew Weissman received the 2023 Nobel Prize in Medicine for foundational work on mRNA vaccines.

Why the other options are wrong

  • (A) mRNA technology does not insert DNA permanently; the CDC explains that vaccine mRNA does not enter the nucleus where DNA is located and is broken down by cells.
  • (C) mRNA does not kill viruses directly; it instructs cells to make a target protein that triggers an immune response.
  • (D) mRNA does not replace the immune system; it helps train or trigger immune responses such as antibody production.

Concept

This tests biotechnology in Science and Technology, especially the distinction between genetic instructions, protein production and immune response. It recurs in RAS because vaccines, public health technology and Nobel-linked scientific advances are common current-affairs anchors.

Source

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